Glucobrassicin Metabolites Ameliorate the Development of ... | 蔬菜好營養
![Glucobrassicin Metabolites Ameliorate the Development of ...](https://i.imgur.com/4LfH9YV.jpg)
由TChang著作·2019·被引用4次—GlucobrassicinMetabolitesAmelioratetheDevelopmentofPortalHypertensionandCirrhosisinBileDuct-LigatedRats.IntJMolSci.
![Glucobrassicin Metabolites Ameliorate the Development of ...](https://i.imgur.com/4LfH9YV.jpg)
Patients suffering from liver cirrhosis are often complicated with the formation of portosystemic collateral vessels, which is associated with the progression of a splanchnic hyperdynamic circulatory state. Alleviating pathological angiogenesis has thus been proposed to be a feasible treatment strategy. Indole-3-carbinol (C9H9NO, I3C) and 3,3-diindolymethane (DIM), formed by the breakdown of glucosinolate glucobrassicin, are prevalent in cruciferous vegetables and have anti-angiogenesis properties. We aimed to evaluate their influences on portal hypertension, the severity of mesenteric angiogenesis, and portosystemic collaterals in cirrhosis. Sprague-Dawley rats with common bile duct ligation (CBDL)-induced liver cirrhosis or sham operation (surgical control) were randomly allocated to receive I3C (20 mg/kg/3 day), DIM (5 mg/kg/day) or vehicle for 28 days. The systemic and portal hemodynamics, severity of portosyste...
CHEBI:29028 - glucobrassicin | 蔬菜好營養
First experimental evidence suggests use of glucobrassicin as ... | 蔬菜好營養
Glucobrassicin | 蔬菜好營養
Glucobrassicin | 蔬菜好營養
Glucobrassicin | 蔬菜好營養
Glucobrassicin Metabolites Ameliorate the Development of ... | 蔬菜好營養
Glucobrassicin | 蔬菜好營養
KEGG COMPOUND | 蔬菜好營養
Showing Compound Glucobrassicin (FDB002066) | 蔬菜好營養
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